In fluentGenomics we explore the use of the Bioconductor packages plyranges and tximeta through integrating results from an experiment using RNA-seq and ATAC-seq data. Readers will learn how to perform genomic range based operations in a principled way using plyranges and how to cleanly import quantification and differential expression data into R using tximeta.


Currently, fluentGenomics is available only on github, install it and associated dependencies with


Once the package has been installed, you can work through the vignette directly from R/Rstudio with:


Or you can read it online here


You can use the package as course material directly with the usethis package: